C010

HER2 Status Determination via Computational Counting of SISH Amplification Signals

Mr. Zaka Ur Rehman, Ir. Prof. Dr. Mohammad Faizal Ahmad Fauzi, Fazley Salleh Abas

AFFILIATION
Faculty of Engineering, Multimedia University

Description of Invention

We propose a computational method for automatic identification and scoring of HER2/CEP17 biomarkers in SISH images. Our system shows high accuracy and concordance (0.91) with manual evaluations, reducing workload for pathologists. Automation speeds up HER2 quantification and ensures consistency in diagnosis. Future enhancements include automated tumor annotation and handling image artifacts.